Sakatole 3-methylindole Skatole

Section 1: Chemical Product and Identification

Product Name & Other Names: 3-Methylindole or Skatole or 3-methyl-1H-indole.
Synonyms: Skatole, Scatole, Skatol, 3-METHYLINDOLE, 3-Methyl-1H-indole, beta-Methylindole, Indole, 3-methyl-, 1H-Indole, 3-methyl-, 3 Methylindole, 3-methylindoline, methyl-3-indole, .beta.-Methylindole, 3-Methyl-4,5-benzopyrrole 3-MI.
CAS#: 83-34-1
EINECS EC Number: 201-471-7
FEMA Number.: 3019
Molecular Weight: 131.17
Chemical Formula: C9-H9-N
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.

Section 2: Hazards Identification

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Skin corrosion/irritation Category 3, H315
Serious eye damage/eye irritation Category 2A, H319
Specific target organ toxicity, single exposure; Respiratory tract irritation Category 3, H335
Hazardous to the aquatic environment, long-term hazard Category 2, H411

Labeling according GHS & Regulation (EC) No 1272/2008

GHS Label Elements Aquatic Toxicity

GHS Label Elements Irritant

Signal Words: Warning

Hazard Statements:
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
H411: Toxic to aquatic life with long lasting effects.

Precautionary Statements:
P264: Wash … thoroughly after handling.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+352: IF ON SKIN: Wash with soap and water.
P332+313: If skin irritation occurs: Get medical advice/attention.
P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
P362: Take off contaminated clothing and wash before reuse.
P391: Collect spillage.
P501: Dispose of contents/container in accordance with local/national regulation.

Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbols:
Xi = Irritant
N = Dangerous for the environment
Risk Phrases:
R36/37/38 = Irritating to eyes, respiratory system and skin.
R51/53 = Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic
environment.

Section 3: Composition and Information on Ingredients

Product Name & Other Names: 3-Methylindole or Skatole or 3-methyl-1H-indole.
CAS Number: 83-34-1
EINECS EC Number: 201-471-7

Section 4: First Aid Measures

Eye Contact: Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes, keeping eyelids open. Cold water may be used. Do not use an eye ointment. Seek medical attention.
Skin Contact: After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin with running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases, and groin. Cover the irritated skin with an emollient. If irritation persists, seek medical attention. Wash contaminated clothing before reusing.
Serious Skin Contact: Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek medical attention.
Inhalation: Allow the victim to rest in a well-ventilated area. Seek immediate medical attention.
Serious Inhalation: Not available.
Ingestion: Do not induce vomiting. Loosen tight clothing such as a collar, tie, belt, or waistband. If the victim is not breathing, perform mouth-to-mouth resuscitation. Seek immediate medical attention.

Section 5: Fire and Explosion Data

Flammability of the Product: May be combustible at high temperature.
Products of Combustion: These products are carbon oxides (CO, CO2), along with some NOx.
Fire Hazards in Presence of Various Substances: Not available.
Fire Fighting Media and Instructions:
SMALL FIRE: Use DRY chemical powder.
LARGE FIRE: Use water spray, fog or foam. Avoid water jet.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.

Section 6: Accidental Release Measures

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill: Do not inhale vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.

Section 7: Handling and Storage

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents and acids. Ground all equipment containing material. Do not ingest.

Section 8: Exposure Controls/Personal Protection

Contains no substances with occupational exposure limit values.
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume, or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Section 9: Physical and Chemical Properties

Physical state and appearance: Whit to off-white solid. (Crystalline solid, flakes or powder).
Odor: Unpleasant.
Odor threshold: Not available.
pH: Not available.
Relative density: Not available.
Boiling Point: 265.5C (509.9F)
Melting Point: 95.5C (203.9F)
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility(ies): Solubility: Partially soluble in hot water, methanol, diethyl ether, n-octanol, acetone. Very slightly soluble in cold water.
Dispersion Properties: Partially dispersed in hot water, n-octanol. Very slightly dispersed in cold water, methanol, and diethyl ether. See solubility in methanol, diethyl ether, n-octanol, and acetone.
Viscosity: Not available.
Molecular Weight: 131.17
Chemical Formula: C9-H9-N

Section 10: Stability and Reactivity Data

Stability: Stable.
Incompatibility with various substances: Reactive with oxidizing agents, acids.
Corrosivity: Not available.
Polymerization: No.

Section 11: Toxicological Information

Toxicity to Animals: Acute oral toxicity (LD50): 3450 mg/kg [Rat].
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Mutagenic Effects: Not available.
Teratogenic Effects: Not available.
Developmental Toxicity: Not available.

Section 12: Ecological Information

Toxicity to fish: LC50 - Pimephales promelas (fathead minnow) - 8,84 mg/l - 96 h
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.

Section 13: Disposal Considerations

Waste Disposal: To be done as per local laws.

Section 14: Transport Information

DOT USA, TDG Canada & ADR/RID Europe
UN number: 3335 Class: 9 Packing group: III
Proper shipping name: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (3-Methylindole)
IMDG/IMO
UN number: 3335 Class: 9 Packing group: III
Proper shipping name: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (3-Methylindole)
IATA
UN number: 3335 Class: 9 Packing group: III
Proper shipping name: Aviation regulated solid, n.o.s. (3-Methylindole)

Section 15: Other Regulatory Information

US Federal and State Regulations:
SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
SARA 313: Not applicable
SARA 311/312: Acute Health Hazard
California Proposition 65: This product does not contain any Proposition 65 chemicals.

16. Other Information

European Labeling in Accordance with EC Directives:
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
H411: Toxic to aquatic life with long lasting effects.

Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbol:
Xi = Irritant
N = Dangerous for the environment
Risk Phrase:
R36/37/38 = Irritating to eyes, respiratory system and skin.
R51/53 = Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic
environment.