Octyl Gallate

Octyl Gallate is the ester of 1-octanol and gallic acid. It is a white powder with a characteristic odor. It is very slightly soluble in water and soluble in alcohol. As a food additive it is used under the E number E311 as an antioxidant and preservative. This antioxidant is used in numerous cosmetics and pharmaceutical, cosmetic, and food products such as soaps, shampoos, shaving soaps, skin lotions, deodorants, margarine, and peanut butter.

General Specifications of Octyl Gallate :
Description: White to creamy white powder, odorless or almost odorless.
Solubility: Insoluble in water, freely soluble in ethanol, ether and propane-1,2-diol
Melting Point: 98C to102C
Gallic Acid: Maximum 0.50%
Organic Chloride :Maximum 100 ppm
Arsenic: Maximum 3 ppm
Heavy Metals: Maximum 10 ppm
Sulphated Ash: Maximum 0.05%
Loss on Drying: Maximum 0.5%
Assay: Minimum 99.00%.

Octyl Gallate BP Grade
Ph Eur
C15H22O5 --- 282.3 --- CAS 1034-01-1

DEFINITION
Octyl 3,4,5-trihydroxybenzoate.
Content: 97.0 per cent to 103.0 per cent (dried substance).

CHARACTERS
Appearance: White or almost white, crystalline powder.
Solubility: Practically insoluble in water, freely soluble in ethanol (96 per cent), practically insoluble in methylene chloride.

IDENTIFICATION
A. Melting point.
Determine the melting point of the substance to be examined. Mix equal parts of the substance to be examined and octyl gallate CRS and determine the melting point of the mixture. The difference between the melting points (which are about 101C) is not greater than 2C.
B. Examine the chromatograms obtained in the test for impurity A.
Results: The principal spot in the chromatogram obtained with test solution (b) is similar in position, colour and size to the principal spot in the chromatogram obtained with reference solution (a).

TESTS
Impurity A: Thin-layer chromatography
Chlorides: Maximum 100 ppm.
Heavy metals: Maximum 10 ppm.
Loss on drying: Maximum 0.5 per cent, determined on 1.000 g by drying in an oven at 70C.
Sulphated ash: Maximum 0.1 per cent, determined on 1.0 g.

ASSAY
Dissolve 0.100 g in methanol and dilute to 250.0 ml with the same solvent. Dilute 5.0 ml of the solution to 200.0 ml with methanol. Measure the absorbance at the absorption maximum at 275 nm.
Calculate the content of C15H22O5 taking the specific absorbance to be 387.

STORAGE
In a non-metallic container, protected from light.

IMPURITIES
Specified impuritiesıA: 3,4,5-trihydroxybenzoic acid (gallic acid).

Certifications :
We manufacture Bulk Drugs / API, Excipients, Pharmaceuticals (IP/BP/USP/NF/Ph. Eur, JP/ CP), Speciality Chemicals(Pure/AR/ACS), Mineral Fortifiers, Food Chemical Codex (FCC) and Flavour chemicals. Our manufacturing facility is cGMP, GLP, ISO 9001, ISO 14001, ISO 22000, ISO/IEC 17025, FSSC 22000, FSSAI, Kosher, HALAL, EXCiPACT, WC, COPP, WHO-GMP and WC certified. We are also REACH registered for export to European countries.