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Calcium Citrate

IP, BP, EP, Ph Eur, USP NF, JP, FCC Food

Calcium Citrate

CAS Number 5785-44-4
Molecular Weight 498.4334 g/mol
Chemical Formula Ca3(C6H5O7)2.4H2O
EINECS EC Number ---
FEMA ---

Calcium citrate is the calcium salt of citric acid. It is commonly used as a food additive (E333), usually as a preservative, but sometimes for flavor. In this sense, it is similar to sodium citrate. Calcium citrate is also used as a water softener because the citrate ions can chelate unwanted metal ions. Calcium citrate is also found in some dietary calcium supplements. Calcium makes up 24.1% of calcium citrate (anhydrous) and 21.1% of calcium citrate (tetrahydrate) by mass.


We offer all grades of Calcium Citrate like Commercial pure, USP & FCC Food grade.



Calcium Citrate USP Grade

C12H10Ca3O14-4H2O -- 570.49
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, calcium salt (2:3), tetrahydrate.
Calcium citrate (3:2), tetrahydrate [CAS 5785-44-4].


Calcium Citrate contains four molecules of water of hydration. When dried at 150 to constant weight, it contains not less than 97.5 percent and not more than 100.5 percent of Ca3(C6H5O7)2.


Identification
A: Dissolve 0.5 g in a mixture of 10 mL of water and 2.5 mL of 2 N nitric acid. Add 1 mL of mercuric sulfate TS, heat to boiling, and add 1 mL of potassium permanganate TS: a white precipitate is formed.
B: Ignite completely 0.5 g at as low a temperature as possible, cool, and dissolve the residue in a mixture of 10 mL of water and 1 mL of glacial acetic acid. Filter, and add 10 mL of ammonium oxalate TS to the filtrate: a voluminous white precipitate is formed, and it is soluble in hydrochloric acid.
Loss on drying: Dry it at 150 for 4 hours: it loses between 10.0% and 13.3% of its weight.
Arsenic: the limit is 3 µg per g.
Limit of fluoride: the limit is 0.003%.
Limit of acid-insoluble substances: Dissolve 5 g by heating with a mixture of 10 mL of hydrochloric acid and 50 mL of water for 30 minutes: the residue so obtained, filtered, washed, and dried at 105 for 2 hours, weighs not more than 10 mg (0.2%).
Lead: the limit is 0.001%.
Heavy metals: the limit is 0.002%.


Calcium Citrate FCC Food Grade
Tricalcium Citrate
CH2(COO)C(OH)(COO)CH2COO2Ca3
Ca3(C6H5O7)2·4H2O Formula weight 570.50
INS: 333 CAS 5785-44-4


DESCRIPTION
Calcium Citrate occurs as a fine, white powder. It is very slightly soluble in water, but it is insoluble in alcohol.


Function: Sequestrant; buffer; firming agent.


REQUIREMENTS
Identification:
A. Dissolve 500 mg of sample in 10 mL of water and 2.5 mL of 1.7 N nitric acid, add 1 mL of mercuric sulfate TS, heat to boiling, and then add potassium permanganate TS. A white precipitate forms.
B. Completely ignite 500 mg of sample at as low a temperature as possible, cool, and dissolve the residue in a mixture of 10 mL of water and 1 mL of glacial acetic acid. Filter, and add 10 mL of ammonium oxalate to the filtrate. A voluminous, white precipitate forms that is soluble in hydrochloric acid.
Assay: Not less than 97.5% and not more than 100.5% of Ca3(C6H5O7)2 after drying.
Fluoride: Not more than 0.003%.
Lead: Not more than 2 mg/kg.
Loss on Drying: Between 10.0% and 14.0%.


Certifications :
We manufacture Bulk Drugs / API, Excipients, Pharmaceuticals (IP/BP/USP/NF/Ph. Eur, JP/ CP), Speciality Chemicals(Pure/AR/ACS), Mineral Fortifiers, Food Chemical Codex (FCC) and Flavour chemicals. Our manufacturing facility is cGMP, GLP, ISO 9001, ISO 14001, ISO 22000, ISO/IEC 17025, FSSC 22000, FSSAI, Kosher, HALAL, EXCiPACT, WC, COPP, WHO-GMP and WC certified. We are also REACH registered for export to European countries.