Benzyl acetone Benzylacetone

Benzylacetone (IUPAC name: 4-phenyl-2-butanone) is a liquid with a sweet, flowery smell that is considered to be the most abundant attractant compound in flowers (e.g. Coyote Tobacco, Nicotiana attenuata) and one of volatile components of cocoa. It can be used as an attractant for melon flies in perfume, and as an odorant for soap.

IUPAC Name: 4-phenylbutan-2-one
CAS No. 2550-26-7
EINECS Number : 219-847-4

Formula:C10H12O
Assay: 99.0% min
Density:0.9875
Odor Type: Floral
Soluble In: Alcohol
Insoluble In: Water
Boiling point: 235-237
Refractive index: 1.51-1.513
Flash point: 98
Water solubility: Practically insoluble

Use: Benzyl acetone is mainly used in synthesis of flavor, pharmaceutical, cosmetic, soap and food with flavor.

Safety:
Most important hazard(s): Xi - Irritant
R 38 - Irritating to skin.
S 02 - Keep out of the reach of children.
S 24 - Avoid contact with skin.
S 36 - Wear suitable protective clothing.
Oral Toxicity(LD50):
Oral-Rat [sex: M] 3200.00 mg/kg
Oral-Mouse 1590.00 mg/kg
Intraperitoneal-Mouse 583.00 mg/kg
Dermal Toxicity(LD50): Skin-Rabbit >5000.00 mg/kg
Inhalation Toxicity(LC50): Not determined

BENZYL ACETONE BENZYLACETONE SDS SAFETY DATA SHEET
MSDS SHEET MATERIAL SAFETY DATA SHEET 07-Dec-20

1. PRODUCT AND COMPANY IDENTIFICATION

Product Name & Other Names: Benzylacetone or Benzyl Acetone.
CAS Number: 2550-26-7
EINECS Number: 219-847-4
FEMA Number: 2588
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.

2. HAZARDS IDENTIFICATION

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Acute toxicity, Oral Category 5, H303
Skin irritation Category 2, H315
Eye irritation Category 2A, H319

Labeling according GHS USA & Regulation (EC) No 1272/2008

GHS Label Elements Irritant

Signal Words: Warning

Hazard statements:
H303: May be harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.

Precautionary statements:
P262: Do not get in eyes, on skin, or on clothing.
P264: Wash skin thoroughly after handling.
P 270: Do not eat, drink or smoke when using this product.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P330: Rinse mouth.
P301+312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302+P352: IF ON SKIN: Wash with soap and water.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.
P332+313: If skin irritation occurs: Get medical advice/attention.
P337+P313: If eye irritation persists: Get medical advice/ attention.
P360: Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.
P362: Take off contaminated clothing and wash before reuse.
P501: Dispose of contents/container to authorized agents.

Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbol:
Symbols: Xi
Risk Phrases:
R36/38 Irritating to eyes and skin.

3. COMPOSITION / INFORMATION ON INGREDIENTS

Product Name & Other Names: Benzylacetone or Benzyl Acetone.
CAS Number: 2550-26-7
EINECS Number: 219-847-4

4. FIRST-AID MEASURES

Always seek medical attention after first aid measures are provided.

Eye Contact: Rinse immediately with plenty of water for 10 minutes at least. Contact a physician if symptoms persist.
Skin Contact: Wash thoroughly with soap and water; flush with plenty of water. Take off spoilt clothes. Contact physician if symptoms persist.
Ingestion: Wash the mouth with water; seek medical advice immediately.
Inhalation: Remove from exposure site to fresh air and keep at rest. Obtain medical advice.

5. FIRE-FIGHTING MEASURES

Recommended Extinguishing Media: CO2, foam, dry chemicals. Avoid solid water stream.
Extinguishing Procedures: Closed containers may build up pressure at elevated temperatures. If possible, containers should be cooled with a water spray.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.

6. ACCIDENTAL RELEASE MEASURES

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep up and remove to an approved disposal container. Avoid open flames or other sources of ignition.

7. HANDLING AND STORAGE

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong acids, alkali, or oxidizing agents. Keep contact to a minimum. Keep away from ignition sources and naked flame.

8. EXPOSURE CONTROL

Exposure Limits: This product does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies.
Respiratory Protection: Avoid to breath directly on the product. Apply local ventilations when appropriate.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

9. PHYSICAL AND CHEMICAL PROPERTIES

Appearance: Colorless liquid
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative density: 0.99
Melting point/freezing point: Not available.
Initial boiling point and boiling range: 235C to 237C.
Flash point: >100C.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility(ies): Not available.
Viscosity: Not available.

10. STABILITY AND REACTIVITY

Reactivity: It presents no significant reactivity hazards. Avoid contact with strong acids, alkali, or oxidizing agents. Avoid heat.
Decomposition: Carbon monoxide and unidentified organic compounds may be formed during combustion.

11. TOXICOLOGICAL INFORMATION

LD 50 ORAL/RAT (mg/Kg): 3200
LD 50 DERMAL/RABBIT (mg/Kg): 5000
Benzyl acetone is irritant to skin, eyes and upper respiratory tract.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.

12. ECOLOGICAL INFORMATION

Toxicity to daphnia and other aquatic invertebrates Immobilization: EC50 - Daphnia magna (Water flea) - > 95.4 mg/l - 48 h.
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.

13. DISPOSAL CONSIDERATIONS

In accordance with local environmental laws. Avoid disposing into drainage or the environment.

14. TRANSPORT REGULATIONS

DOT USA, TDG Canada & ADR/RID Europe:
Not regulated as dangerous goods.
IMDG/IMO & IATA/ICAO:
Not regulated as dangerous goods.

15. REGULATORY INFORMATION

USA regulations:
Superfund Amendments and Reauthorization Act of 1986 (SARA): Immediate Hazard
SARA 302 Extremely hazardous substance: Not listed.
SARA 313 (TRI reporting): Not regulated.
US - California Proposition 65 - Carcinogens & Reproductive Toxicity (CRT): Not listed.