| CAS No.: | 69-72-7 |
| Molecular Weight: | 138.12 g/mol |
| Chemical Formula | C7H6O3 |
Salicylic acid is used in the production of other pharmaceuticals. Salicylic acid as a medication is used most commonly to help remove the outer layer of the skin. As such, it is used to treat warts, psoriasis, acne vulgaris, ringworm, dandruff, and ichthyosis. Salicylic acid is also used as a food preservative, bactericide, and an antiseptic.
Salicylic Acid BP Ph Eur Specifications:
C7H6O3 --- 138.1 --- CAS 69-72-7
Action and use: Keratolytic.
DEFINITION
2-Hydroxybenzenecarboxylic acid.
Content: 99.0 per cent to 100.5 per cent (dried substance).
CHARACTERS
Appearance: White or almost white, crystalline powder or white or colourless, acicular crystals.
Solubility: Slightly soluble in water, freely soluble in ethanol (96 per cent), sparingly soluble in methylene chloride.
IDENTIFICATION
First identification: A, B
Second identification: A, C
A. Melting point: 158C to 161C.
B. Infrared absorption spectrophotometry
C. Dissolve about 30 mg in 5 mL of 0.05 M sodium hydroxide, neutralise if necessary and dilute to 20 mL with water. 1 mL of the solution gives reaction (a) of salicylates.
TESTS
Solution S: Dissolve 2.5 g in 50 mL of boiling distilled water, cool and filter.
Appearance of solution: The solution is clear and colourless.
Dissolve 1 g in 10 mL of ethanol (96 per cent).Related substances: To pass the test.
Chlorides: Maximum 100 ppm.
Sulfates: Maximum 200 ppm.
Loss on drying: Maximum 0.5 per cent, determined on 1.000 g by drying in a desiccator.
Sulfated ash: Maximum 0.1 per cent, determined on 2.0 g.
Salicylic Acid USP Grade Specifications:
C7H6O3 --- 138.12
Benzoic acid, 2-hydroxy-
Salicylic acid CAS 69-72-7
DEFINITION
Salicylic Acid contains NLT 98.0% and NMT 102.0% of salicylic acid (C7H6O3 ), calculated on the dried basis.
IDENTIFICATION
A. Infrared Absorption
B. The retention time of the major peak of the Sample solution corresponds to that of the Standard solution, as obtained in the Assay.
ASSAY
To pass the test.
Acceptance criteria: 98.0%–102.0% on the dried basis.
Residue on Ignition: NMT 0.05%
Chloride and Sulfate:
Chloride: To pass the test (0.014%).
Sulfate: To pass the test (0.02%).
Organic Impurities: To pass the test.
Loss on Drying:
Analysis: Dry over silica gel for 3 h.
Acceptance criteria: NMT 0.5%
Salicylic Acid Analytical Reagent Grade:
2-Hydroxybenzoic Acid
C7H6O3 --- Formula Weight 138.12
CAS Number 69-72-7
REQUIREMENTS
Assay: 99.0% C7H6O3
Melting point: 158C-161C
We also Supply IP Grade of Salicylic Acid.
