| CAS No.: | 141-78-6 |
| Molecular Weight: | 88.10 g/mol |
| Chemical Formula | C4H8O2 |
Ethyl acetate or Ethyl ethanoate is the organic compound with the formula C4H8O2. This colorless liquid has a characteristic sweet fruity smell and is used in glues, nail polish removers, and in the decaffeination process of tea and coffee. Ethyl acetate is used primarily as a solvent and diluent. It is commonly used to clean circuit boards and in some nail varnish removers. It is also used in paints. Ethyl acetate is present in confectionery, perfumes, and fruits. It has E number of E1504.
General Properties and Specifications of Ethyl acetate or Ethyl ethanoate:
Appearance: Colorless liquid.
Assay: 99.5%
Odor: Sweet fruity odor.
Relative density: about 0.9
Melting point: -84C.
Boiling point: 77C.
Flash point: -4C.
Autoignition temperature: 427C.
Solubility: Soluble in water. Miscible with ethanol, acetone, and benzene.
Ethyl Acetate USP NF Grade Specifications:
C4H8O2 --- 88.11
Acetic acid, ethyl ester;
Ethyl acetate CAS 141-78-6
DEFINITION
Ethyl Acetate contains NLT 99.0% and NMT 100.5% of ethyl acetate (C4H8O2).
IDENTIFICATION
A. Infrared Absorption
ASSAY
To pass the test by titrimetry.
Acceptance criteria: 99.0% to 100.5%
Limit of Nonvolatile Residue:
Sample: Ethyl Acetate
Analysis: Evaporate the Sample in a tared porcelain dish on a steam bath, and dry at 105° for 1 h.
Acceptance criteria: NMT 0.02%
Limit of Methyl Compounds: To pass the test.
Chromatographic Purity: To pass the test.
Acceptance criteria: The area of the ethyl acetate peak is NLT 99.5% of the sum of the areas of all the peaks.
Acidity:
Sample solution: 2.0 mL of Ethyl Acetate in 10 mL of neutralized alcohol
Analysis: Add 2 drops of phenolphthalein to the Sample solution. Neutralize with 0.10 N sodium hydroxide.
Acceptance criteria: NMT 0.10 mL of 0.10 N sodium hydroxide is required.
Readily Carbonizable Substances Test:
Sample: 2 mL of Ethyl Acetate
Analysis: Add the Sample carefully to 10 mL of sulfuric acid to form separate layers.
Acceptance criteria: No dark zone is developed within 15 min.
Specific Gravity: 0.894–0.898
Packaging and Storage: Preserve in tight containers and avoid exposure to excessive heat.
Ethyl Acetate BP Ph Eur Specifications:
C4H8O2 --- 88.1 --- CAS 141-78-6
Action and use: Excipient.
DEFINITION
Ethyl ethanoate.
CHARACTERS
Appearance: Clear, colourless, volatile liquid.
Solubility: Soluble in water, miscible with acetone, with ethanol (96 per cent) and with methylene chloride.
IDENTIFICATION
First identification: B
Second identification: A, C, D
A. Boiling point: 76 °C to 78 °C.
B. Infrared absorption spectrophotometry.
C. It gives the reaction of acetyl.
D. It gives the reaction of esters.
TESTS
Appearance of solution: The solution is clear and colourless.
Mix 1 mL of the substance to be examined and 15 mL of water.
Acidity: To 10 mL of ethanol (96 per cent) add 0.1 mL of phenolphthalein solution and 0.01 M sodium hydroxide until the colour changes to pink. Add 5.5 mL of the substance to be examined and 0.25 mL of 0.02 M sodium hydroxide. The solution remains pink for not less than 15 s.
Relative density: 0.898 to 0.902.
Refractive index: 1.370 to 1.373.
Reaction with sulfuric acid: Carefully add 2 mL to 10 mL of sulfuric acid. After 15 min, the interface between the 2 liquids is not coloured.
Related substances: to pass the test by Gas chromatography.
Limit: --total: not more than 0.2 per cent of the area of the principal peak.
Residue on evaporation: Maximum 30 ppm.
Evaporate 100.0 g to dryness on a water-bath and dry in an oven at 100-105 °C. The residue weighs not more than 3 mg.
Water: Maximum 0.1 per cent, determined on 10.0 mL.
STORAGE
Protected from light, at a temperature not exceeding 30C.
Ethyl Acetate Analytical Reagent Grade Specifications:
CH3COOCH2CH3 --- Formula Weight 88.11
CAS Number 141-78-6
Suitable for use in ultraviolet spectrophotometry or general use. Product labeling shall designate the one or both of these uses for which suitability is represented on the basis of meeting the relevant requirements and tests. The ultraviolet spectrophotometry requirements include all of the requirements for general use.
REQUIREMENTS
Assay: 99.5% CH3COOCH2CH3
