| CAS No.: | 2016-36-6 |
| Molecular Weight: | 241.28 g/mol |
| Chemical Formula | C12H19NO4 |
Choline Salicylate Solution BP Ph Eur Grade Specifications:
Action and use: Salicylate; non-selective cyclo-oxygenase inhibitor; analgesic; anti-inflammatory.
DEFINITION
Choline Salicylate Solution is an aqueous solution of choline salicylate. It contains not less than 47.5% w/v and not more than 52.5% w/v of choline salicylate, C12H19NO4. It may contain a suitable antimicrobial preservative.
CHARACTERISTICS
A clear, colourless liquid.
IDENTIFICATION
A. Mix 0.5 mL with 10 mL of methanol, dry with anhydrous sodium sulfate, filter and evaporate the methanol to dryness. The infrared absorption spectrum of the residue is concordant with the reference spectrum of choline salicylate.
B. Dilute 5 mL to 25 mL with water. The resulting solution yields the reactions characteristic of salicylates.
TESTS
Acidity: Dilute 4 mL to 20 mL with water and add 0.1 mL of phenol red solution. The solution is yellow and not more than 0.4 mL of 0.1M sodium hydroxide is required to change the colour of the solution to reddish violet.
Clarity and colour of solution: Dilute 1 volume of the solution to 5 volumes with water. The resulting solution is clear and colourless,
Weight per mL: 1.070 to 1.110 g.
Chloride: To pass the test.
