| CAS No.: | 75-65-0 |
| Molecular Weight: | 74.12 g/mol |
| Chemical Formula | (CH3)3COH or C4H10O |
10x TBE Buffer pH-8.3 SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 16-Nov-23
1. Product Identification
Product Name & Other Names: 10x TBE Buffer pH-8.3
CAS No.: NA
EINECS EC Number: NA
Molecular Weight: NA
Chemical Formula: NA
Relevant uses and uses advised against (if any): Industrial use only.
Supplier: As per letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Reproductive toxicity Category 1A, 1B - H360
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements  Health Hazard |
Signal Words: Danger
Hazard statements:
H360: May damage fertility or the unborn child
Precautionary statements:
P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P281: Use personal protective equipment as required.
P308+313: IF exposed or concerned: Get medical advice/attention.
P405: Store locked up.
P501: Dispose of contents/container to authorized agents only.
Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbol:
Xn = Harmful
Risk Phrases:
R60 = May impair fertility.
R61 = May cause harm to the unborn child.
Products containing Boric Acid are not intended for ingestion. Boric Acid has a low acute toxicity. Small amounts swallowed accidentally are not likely to cause effects; swallowing large amounts may cause gastrointestinal symptoms.
3. Composition/Information on Ingredients
Product Name & Other Names: 10x TBE Buffer pH-8.3
CAS No.: NA
EINECS EC Number: NA
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician.
Ingestion: Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt, or waistband. Get medical attention if symptoms appear.
Skin Contact: Remove any contaminated clothing. Wash skin with soap or mild detergent and water for at least 15 minutes. Get medical attention if irritation develops or persists. Wash cloths and Shoes before re-use.
Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush your eyes with plenty of water for at least 15 minutes. Cold water may be used. Get medical attention.
Note to physicians: Observation only is required for adult ingestion of less than 6 grams of boric acid. For ingestion more than 6 grams, maintain adequate kidney function and force fluids. Gastric lavage is recommended for symptomatic patients only.
5. Fire Fighting Measures
Fire: It is not considered to be a fire hazard. However, it can burn at high temperature.
Fire Extinguishing Media: Use any means suitable for extinguishing surrounding fire. Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide.
Special hazards arising from the substance or mixture: Borane/boron oxides
Extinguishing Media Not recommended: Avoid using solid water jet as it may scatter the fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and a suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Ventilate area of leak or spill. Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal. Finish cleaning by spreading water on the contaminated surface and dispose of according to legal authority requirements.
Large Spill: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials. Keep in a well closed container stored under cold to condition. Storage: 2 to 8C (Refrigerate).
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: No information found.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator (NIOSH type N95 or better filters) may be worn. If oil particles (e.g., lubricants, cutting fluids, glycerin, etc.) are present, use a NIOSH type R or P filter. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection: Gloves and lab coat, apron, or coveralls.
Eye Protection: Use chemical safety goggles. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9. Physical and Chemical Properties
Appearance: Clear colourless liquid.
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative density: Not available.
Boiling Point: Not available.
Melting Point: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor Pressure (mm Hg): Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Not available.
Viscosity: Not available.
Molecular Weight: NA
Chemical Formula: NA
10. Stability and Reactivity
Stability: It is stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: Carbon oxides, unidentified fumes, and Boron compounds.
Hazardous Polymerization: Will not occur.
Incompatibilities: Oxidizing agents.
Conditions to avoid: Heat. Avoid dust formation. Dust may form explosive mixture in air. Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard. Incompatible materials.
11. Toxicological Information
Toxicological Data: Not available.
Oral woman LDLo: Boric acid investigated as a mutagen, tumorigen, reproductive effector.
Reproductive Toxicity: May impair fertility. May cause harm to the unborn child.
Carcinogenic Effects: Not a reported carcinogen by IARC, NTP, ACGIH, OSHA.
12. Ecological Information
Toxicity to fish: No information available.
Environmental Toxicity: This material may be toxic to aquatic life.
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with law.
14. Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not dangerous goods.
IMDG/IMO: Not dangerous goods.
IATA/ICAO: Not dangerous goods.
15. Regulatory Information
It should be noted that borates are safe under conditions of normal handling and use. They are essential nutrients to plants, and research shows that they play a beneficial role in human health.
USA:
SARA 311/312: Chronic Health Hazard. See section 2.
California Prop. 65 Components: This product does not contain any chemicals known to the State of California to cause cancer, birth defects, or any other reproductive harm.
16. Other Information
European Labeling in Accordance with EC Directives:
H360 = May damage fertility or the unborn child
Disclaimer:
